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The Leysian Mission was started in 1886 by former pupils of the Leys School who were concerned about the social and housing conditions in the East End of London. It’s first premises were in nearby Whitecross Street but in 1902 the Mission moved into grand purpose-built premises in Old Street (just round the corner from Wesley’s Chapel). It had vibrant evangelical and social ministries and encouraged alumni from the Cambridge school to give time to programmes that reached out to the poor; It touched the lives of thousands of people. In the early days, there was a Medical Mission, a “poor man’s lawyer”, a relief committee, feeding programmes, meetings for men and women, and a range of services and musical activities.

In the late 1990's the building was converted to apartments.

Source: http://www.wesleyschapel.org.uk/mission.htm